Solutions for Pharmacovigilance

Safety regulatory
intelligence, automated

Never miss a PRAC recommendation, safety communication, or labeling change again. RegNexia AI monitors global safety regulators continuously so your PV team can act fast on what matters most.

50+

Safety authorities monitored

4

Continents of coverage

24/7

Continuous monitoring

AI

Powered summaries

Challenges

Safety monitoring is too critical to do manually

PRAC and safety committee updates are scattered and delayed

Automated monitoring of EMA PRAC, FDA Drug Safety Communications, and all major safety bodies surfaces updates within hours of publication.

Labeling changes require constant cross-market vigilance

Track SmPC, USPI, and regional labeling updates simultaneously across all markets where your products are approved.

Adverse event reporting requirements differ by jurisdiction

AI classifies each update by topic — including adverse event reporting, signal assessment, and REMS — so your team acts on the right information.

Signal assessment and benefit-risk documents are hard to track

Detect changes to PSURs, PASSes, risk management plans, and benefit-risk assessments the moment they are published or updated.

Capabilities

Built for the complexity of PV monitoring

PRAC Recommendation Tracking

Monitor EMA Pharmacovigilance Risk Assessment Committee recommendations, safety referrals, and post-authorisation safety studies in real time.

Safety Communication Alerts

Receive instant alerts for FDA Drug Safety Communications, DHPC letters, Dear Healthcare Provider letters, and urgent safety restrictions.

Labeling Change Detection

Detect amendments to SmPCs, USPIs, package inserts, and patient information leaflets across all monitored jurisdictions simultaneously.

Adverse Event Reporting Updates

Track changes to expedited reporting timelines, E2B submission formats, MedWatch requirements, and EudraVigilance reporting obligations.

Risk Management Plan Monitoring

Stay current on evolving RMP templates, additional risk minimisation measures, and post-marketing commitments from regulators globally.

Signal & Benefit-Risk Intelligence

Monitor WHO-UMC signal notifications, FDA Sentinel updates, and EMA signal assessment reports to stay ahead of emerging safety concerns.

Use Cases

How PV teams use RegNexia

Pharmacovigilance Director

Receives a prioritized daily safety regulatory digest covering PRAC outcomes, new safety referrals, and urgent labeling changes — across every market at once.

Signal Management Lead

Monitors WHO-UMC ICSRs and FDA Sentinel system updates to identify emerging signals before they escalate to regulatory action.

Safety Labeling Manager

Gets an alert the moment a competitor product's label is updated for a class-wide safety issue, enabling proactive label review for their own portfolio.

PSUR / Periodic Report Coordinator

Tracks EPAR updates, PSUR worksharing procedure outcomes, and PBRER submissions to align their reporting calendar with the latest regulator expectations.

Coverage

Safety authorities tracked globally

From PRAC sessions in Amsterdam to FDA safety communications in Washington, RegNexia captures every safety signal from every major authority.

EMA / PRACFDA MedWatchMHRA Yellow CardHealth CanadaTGAPMDACDSCOWHO-UMCEudraVigilanceANVISABfArMANSMMFDSHSASwissmedic

Topics

PV-specific topic classification

Every update is auto-classified by PV topic so your team spends zero time sorting through irrelevant content.

PRAC RecommendationsSafety ReferralsDrug Safety CommunicationsDHPC LettersSmPC / USPI UpdatesRMP AmendmentsAdverse Event ReportingSignal AssessmentsREMS ProgramsPost-Marketing CommitmentsBenefit-Risk EvaluationsEudraVigilance

Protect patients. Stay ahead of regulators.

See how RegNexia AI helps your Pharmacovigilance team detect safety regulatory changes before they become compliance incidents.

No credit card required. See the platform in under 30 minutes.